CTT2274

SKU: orb2944904

Description

CTT2274 is a PSMA-targeted prodrug of MMAE, utilizing a pH-sensitive phosphoramidate linker for selective payload delivery. It is applied in prostate cancer research, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.

Research Area

Immunology & Inflammation

Key Properties

• MW: 2417.58
• Formula: C₁₁₉H₁₅₉N₁₇O₃₃P₂
• SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)OC(=O)N(C)CCN(C)P(=O)(O)OCC[C@@H](C(=O)O)NC(=O)C4=CC=C(C=C4)CN5C6=C(C7=CC=CC=C7N(CC8=CC=CC=C86)C(=O)CCC(=O)N[C@@H](CC9=CC=C(C=C9)C1=CC=CC=C1)C(=O)NCCCCCC(=O)N[C@@H](CCC(=O)N[C@@H](CCCOP(=O)(N[C@@H](CCC(=O)O)C(=O)O)O)C(=O)O)C(=O)O)N=N5
• Target: PSMA

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676895