CT20p

SKU: orb3142468

Description

CT20p is an anticancer peptide derived from the hydrophobic terminal of BaxC. It exhibits a unique cytotoxic effect independent of the full-length Bax, targeting mitochondria to induce fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p reduces α5β1 integrin levels, inhibits F-actin polymerization, thus disrupting the cytoskeleton and preventing cell adhesion. CT20p is applicable in breast cancer research.

Research Area

Cell Biology

Key Properties

• Target: Bcl-2 Family
• CAS Number: 1407967-57-0
• MW: 2176.66
• Formula: C₁₀₃H₁₇₀N₂₄O₂₅S
• SMILES: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N)=O)=O)CCSC)=O)CCCCN)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)=O)[C@H](C)C)=O)C)=O)=O)[C@@H](C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)C)=O)CO)=O)CC(C)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)C=2C=3C(NC2)=CC=CC3

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bcl-2 Family