CT 32228

SKU: orb3174349

Description

CT 32228 is an inhibitor of LPAAT-β. It effectively suppresses tumor cell proliferation and has an IC50 ranging from 0.1 to 0.8 μM in various leukemia cell lines. CT 32228 induces caspase activation in DHL-4 and Ramos cells. When used in combination with Rituximab, it promotes apoptosis. In vivo studies demonstrate that CT 32228 can delay xenograft tumor growth by 50%. This compound is applicable in research related to acute leukemia.

Research Area

Cell Biology

Key Properties

• CAS Number: 521064-34-6
• MW: 390.67
• Formula: C₁₆H₁₃BrClN₅
• SMILES: ClC=1C=CC(=C(C1)C=2N=C(N=C(N2)NC3=CC=C(Br)C=C3)N)C
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis