CSN5-IN-1

SKU: orb2663591

Description

CSN5-IN-1 (Ac-11) is a CSN5 inhibitor with IC50 values of 12.56 μM (FP assay) and 19 μM (fluorescence assay). It modulates cellular protein levels, reducing PD-L1 and increasing NEDD8-Cul1, making it a useful probe for studying COP9 signalosome function in cancer immunology and protein neddylation pathways.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry

Key Properties

• MW: 318.43
• Formula: C₁₇H₂₂N₂O₂S
• Target: E1/E2/E3 Enzyme,Others,PD-1/PD-L1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E1/E2/E3 Enzyme,Others,PD-1/PD-L1