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CSBP ligand 1

SKU: orb3173709

Description

CSBP ligand 1 (Compound 36) is a ligand for CSBP, exhibiting an IC50 of 0.08 μM for CSBP binding. In mice treated with LPS, CSBP ligand 1 suppresses TNF production. It shows no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be utilized in research on inflammation-related diseases.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number165806-32-6
MW279.32
FormulaC17H14FN3
SMILESFC1=CC=C(C=C1)C=2N=CN(C2C=3C=CN=CC3)C4CC4
TargetLipoxygenase,Serine/threonin kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information