CRT5

SKU: orb1704964

Description

CRT5 is a potent, selective pyrazine benzamide inhibitor of PKD isoforms (IC50s 1-2 nM). It blocks VEGF-induced phosphorylation of HDAC5, CREB, and HSP27, and inhibits endothelial cell migration, proliferation, and tubulogenesis in vitro, making it a valuable research tool for studying angiogenesis and PKD signaling pathways.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1034297-58-9
• MW: 454.56
• Formula: C₂₈H₃₀N₄O₂
• SMILES: NC1=C(C=C(C=N1)C2=CC(C(NCCN(C)C)=O)=CC=C2)C3=CC4=C(C=C3)C=C(OCC)C=C4
• Target: Serine/threonin kinase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

58238286