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CRT0066101

CRT0066101

Catalog Number: orb2566590

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Catalog Numberorb2566590
CategorySmall Molecules
DescriptionCRT0066101 is a potent, orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM, and 2 nM for PKD1, PKD2, and PKD3, respectively [1]. Additionally, it inhibits PIM2 with an IC 50 of approximately 135.7 nM and demonstrates anticancer effects [2].
CAS Number956123-34-5
Purity98.00%
MW338.41
SMILESOC=1C(=CC(=CC1)C2=CN(C)N=C2)C=3N=C(NC[C@@H](CC)N)C=CN3
FormulaC18H22N6O
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • CRT0066101 hydrochloride [orb2283813]

    98.00%

    1781742-22-0

    374.87

    C18H23ClN6O

    10 mg, 50 mg
  • PKD-IN-1 [orb1685338]

    98%

    956121-30-5

    342.82

    C18H19ClN4O

    100 mg, 50 mg, 25 mg, 10 mg, 5 mg
  • CRT0066101 dihydrochloride [orb1296201]

    99.85%

    1883545-60-5

    411.33

    C18H24Cl2N6O

    25 mg, 5 mg, 10 mg, 50 mg, 1 mg, 1 ml x 10 mm (in DMSO)
  • PKD-IN-1 dihydrochloride (956121-30-5 free base) [orb1298493]

    99.50%

    2308510-39-4

    415.75

    C18H21N4OCl3

    50 mg, 25 mg, 5 mg, 2 mg, 1 ml x 10 mm (in DMSO), 100 mg, 10 mg
  • CRT0066101 [orb2279736]

    [956121-30-5]

    342.822662591934

    C18H19CLN4O

    100 mg, 250 mg, 1 g