Crocin II

SKU: orb1303760

Description

Crocin II exhibits anti-inflammatory, anti-apoptotic, and antioxidant properties, demonstrated in models of gastric and hepatic injury. Its mechanisms involve modulating iNOS, caspase-3, and inflammatory cytokines. Research applications include studying metabolic disorders, neuroprotection, and ischemia-reperfusion injury in both in vivo and in vitro experimental systems.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Protein Biochemistry

Key Properties

• CAS Number: 55750-84-0
• MW: 814.82
• Purity: 99.19% (May vary between batches)
• Formula: C₃₈H₅₄O₁₉
• SMILES: C\C(\C=C\C=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=C/C=C/C=C(\C)/C=C/C=C(\C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
• Target: COX,Endogenous Metabolite,NO Synthase,Caspase
• Solubility: DMSO:120 mg/mL (147.27 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.45 mM)

Bioactivity

• Target IC50:
  NO production:31.3 μM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tricrocin, caspase, COX, Crocetin gentiobiosylglucosyl ester, Crocin 2, Crocin B, Crocin II, Cyclooxygenase, NOS, NOSynthase, inhibit, Nitric oxide synthases, NO Synthase, Inhibitor

Compound Identifiers

PubChem CID

9940690