Cristacarpin

SKU: orb1682886

Description

Cristacarpin

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 74515-47-2
• MW: 354.4
• Formula: C₂₁H₂₂O₅
• SMILES: O[C@]12[C@](C=3C(OC1)=CC(O)=CC3)(OC=4C2=CC=C(OC)C4CC=C(C)C)[H]
• Target: Antibacterial,ROS

Bioactivity

• In Vivo:
  Methods: Cristacarpin (0.1-10 μM) was used to treat three different moderately invasive cell lines, PANC-1, MCF-7 and PC3, and cell proliferation was determined by MTT. Results: The IC50 values ​​of Cristacarpin for the three cell lines were 6.3, 6.6 and 10.23 μM.
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• In Vitro:
  Methods AND Results: Bioactivity-directed fractionation of the CHCl3 extract of the bark of Erythrina burana afforded phaseollidin and Cristacarpin . Both 1 and Cristacarpin exhibited moderate but selective activity towards DNA repair-deficient yeast mutants, whereas only 1 was found to be cytotoxic. 13C-nmr spectra of both compounds were assigned.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p21, p38 MAPK, p38MAPK, ROS, Erythrabissin I, Erythrabyssin I, p53, Antifection, Cristacarpin, Cdk

Compound Identifiers

PubChem CID

126540