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CRBN modulator-1

SKU: orb1298606

Description

WUN29654 is a thalidomide-based CRBN modulator with a Ki of 0.98 µM and an IC50 of 3.5 µM. This small molecule is used in biochemical and cellular research to study targeted protein degradation and probe CRBN-dependent pathways in vitro.

Research Area

Cancer Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2407829-65-4
MW324.288
Purity99.55% (May vary between batches)
FormulaC17H12N2O5
SMILESO=C1NC(=O)C(N2C(=O)C=3C=CC=C4C=C(O)C=C(C2=O)C43)CC1
TargetLigands for E3 Ligase
SolubilityDMSO:3.25 mg/mL (10.02 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CRBN modulator 1, CRBN modulator1, CRBN modulator-1, E3 ligase-recruiting Moiety, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, inhibit, Inhibitor, WUN 29654, WUN29654, WUN-29654

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 120.00
25 mg
$ 180.00
50 mg
$ 240.00
100 mg
$ 330.00
DispatchUsually dispatched within 5-10 working days
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