Vorbipiprant

SKU: orb1738762

Description

CR6086 is a potent and selective EP4 receptor antagonist with a Ki of 16.6 nM, effectively blocking PGE2-induced cAMP signaling. It demonstrates immunomodulatory and anti-inflammatory properties distinct from COX inhibitors, showing disease-modifying antirheumatic drug (DMARD) effects in rodent models of immune-mediated inflammatory diseases.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1417742-86-9
• MW: 472.5
• Formula: C₂₆H₂₇F₃N₂O₃
• SMILES: O=C(O)C1=CC=C(C=C1)C2(NC(=O)C3N(CC4=CC=C(C=C4)C(F)(F)F)CCC5(CC5)C3)CC2
• Target: Prostaglandin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71186236