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CQ-16

SKU: orb2802427

Description

CQ-16 is an orally bioavailable small molecule drug conjugate (SMDC) targeting PSMA with high selectivity for PSMA-positive prostate cancer cells. It also functions as a potent PARP inhibitor (IC50=1 nM), supporting its investigation in targeted therapy and combination strategies for prostate cancer research in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3024354-59-1
MW850.85
FormulaC40H47FN8O12
SMILESC(=O)(C1(NC(CCC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=O)CC1)N2CCN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)CC2
TargetPROTACs,PSMA,PARP,Epigenetic Reader Domain

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information