CPUL1

SKU: orb1744080

Description

CPUL1 is a thioredoxin reductase (TrxR) inhibitor that suppresses proliferation and metastasis in A549 lung cancer cells. It induces ROS-mediated ERK/JNK signaling to modulate epithelial-mesenchymal transition (EMT). Its anti-tumor activity is further potentiated in combination with α-Lipoic Acid or Dithiodipropionic acid, supporting its investigation in oncology research.

Key Properties

• CAS Number: 2043660-80-4
• MW: 434.28
• Formula: C₂₂H₁₃Cl₂N₅O
• SMILES: C(#N)C=1C(C2=C3C(N=C4C(=N3)C=CC=C4)=CC(N)=C2OC1N)C5=CC(Cl)=C(Cl)C=C5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137645134