CPI-455 HCl

SKU: orb1704835

Description

CPI-455 is a potent and selective KDM5 inhibitor with an IC50 of 10 nM against KDM5A. It increases global H3K4me3 levels and reduces drug-tolerant persister (DTP) cells in vitro, supporting research into epigenetic mechanisms in cancer therapy resistance.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2095432-28-1
• MW: 314.77
• Formula: C₁₆H₁₅ClN₄O
• SMILES: Cl.CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
• Target: Histone Demethylase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129896721