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CPI-455 HCl

SKU: orb1704835

Description

CPI-455 is a potent and selective KDM5 inhibitor with an IC50 of 10 nM against KDM5A. It increases global H3K4me3 levels and reduces drug-tolerant persister (DTP) cells in vitro, supporting research into epigenetic mechanisms in cancer therapy resistance.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2095432-28-1
MW314.77
FormulaC16H15ClN4O
SMILESCl.CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
TargetHistone Demethylase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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CPI-455 HCl (orb1704835)

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