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CPD-10

SKU: orb2802390

Description

CPD-10 is a potent bifunctional PROTAC molecule that selectively degrades CCND1 and CDK4. It demonstrates dose-dependent antiproliferative effects in vitro by reducing Cyclin D1, Cyclin D3, CDK4, and phospho-Rb protein levels, leading to cell cycle arrest and apoptosis. This tool compound is suitable for cancer research, particularly in studying CDK4/6 pathway dysregulation.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3055471-57-0
MW888.08
FormulaC46H61N15O4
SMILESO=C(NC1=NN=C(C=C1)N(C)C)C2=CC=C(N=C2NCCCCCCCNC(=O)CN3CCN(C4=CN=C(C=C4)NC=5N=CC6=C(N5)N(C(=O)C(C(=O)C)=C6C)C7CCCC7)CC3)NC
TargetGlucocorticoid Receptor,PROTACs,CDK,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information