COX-2/sEH-IN-1

SKU: orb1686645

Description

COX-2/sEH-IN-1 is an orally bioavailable small molecule that dually inhibits cyclooxygenase-2 (IC50=1.24 µM) and soluble epoxide hydrolase (IC50=0.40 µM). This dual pharmacological action is investigated in research models for its potential to modulate inflammation and provide cardiovascular protection, as suggested by in vitro and preclinical in vivo studies.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 2474977-38-1
• MW: 501.48
• Formula: C₂₃H₁₈F₃N₅O₃S
• SMILES: N(C(NC1=CC=C(C(F)(F)F)C=C1)=O)C2=NN(C(=C2)C3=CC=CC=C3)C4=CC=C(S(N)(=O)=O)C=C4
• Target: Others,COX,Epoxide Hydrolase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162666184