COX-2/CaV2.2-IN-1

SKU: orb3210360

Description

COX-2/CaV2.2-IN-1 is an orally active, selective dual-target inhibitor of COX-2 and CaV2.2, with an IC50 of 0.26 μM for COX-2 and 0.29 μM for CaV2.2. It effectively suppresses inflammatory responses and the production of inflammatory mediators (IL-6, TNF-α, NO). This compound demonstrates significant analgesic effects in various models of inflammatory pain, neuropathic pain, and visceral pain, making it a valuable tool for research in chronic pain-related studies.

Key Properties

• Target: COX,Interleukin,TNF,Calcium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

COX,Interleukin,TNF,Calcium Channel