COX-2-IN-48

SKU: orb2665202

Description

COX-2-IN-48 (5-25) is a potent and selective COX-2 inhibitor (IC50 = 51.7 nM) with demonstrated anti-inflammatory and analgesic activity in rodent models. Its mechanism involves suppressing the NF-κB pathway, thereby inhibiting IκB degradation, p65 nuclear translocation, and downstream expression of COX-2 and iNOS.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction

Key Properties

• Target: COX,NO Synthase,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

COX,NO Synthase,NF-κB