COX-2-IN-32

SKU: orb1944330

Description

COX-2-IN-32 (2f) is a dual iNOS/COX-2 inhibitor that suppresses NF-κB signaling. It exhibits anti-inflammatory activity by inhibiting nitric oxide production in LPS-stimulated RAW264.7 macrophages with an IC50 of 11.2 µM, making it a useful research tool for studying inflammation in cellular models.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 2725863-08-9
• MW: 420.45
• Purity: 98.11% (May vary between batches)
• Formula: C₂₅H₂₄O₆
• SMILES: C(/C=C/C1=CC=C(OC2=CC=C(OC)C=C2)C=C1)(=O)C3=CC(OC)=C(OC)C(OC)=C3
• Target: COX

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168058202