Coumarin-3-carboxylic acid

SKU: orb1297681

Description

The combination of Valproic acid and Coumarin-3-carboxylic acid inhibits lung cancer cell proliferation and migration by targeting EGFR/VEGFR2/c-Met-Akt-NF-κB signaling. This synergistic pair is a valuable research tool for investigating novel therapeutic strategies in oncology, with applications in both in vitro and in vivo cancer models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 531-81-7
• MW: 190.15
• Purity: 99.88% (May vary between batches)
• Formula: C₁₀H₆O₄
• SMILES: OC(=O)C1=CC2=C(OC1=O)C=CC=C2
• Target: Others,VEGFR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.52 mM);DMSO:50 mg/mL (262.95 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3-Carboxycoumarin, Coumarin 3 carboxylic acid, Coumarin3carboxylic acid, Coumarin-3-carboxylic acid, Inhibitor, inhibit, VEGFR

Compound Identifiers

PubChem CID

10752