Cornuside

SKU: orb1302280

Description

Cornuside is a bioactive small molecule with demonstrated immunomodulatory and anti-inflammatory properties. It exerts its effects by inhibiting key pro-inflammatory pathways, including NF-κB and MAPK signaling, and has shown protective potential in research models of cerebral ischemia, myocardial ischemia-reperfusion, and chemical-induced hepatotoxicity both in vitro and in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 131189-57-6
• MW: 542.49
• Purity: >99.99% (May vary between batches)
• Formula: C₂₄H₃₀O₁₄
• SMILES: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](C=C)[C@@H]1CCOC(=O)c1cc(O)c(O)c(O)c1
• Target: JNK,ERK,p38 MAPK,NF-κB
• Solubility: Pyridine, Methanol, etc.:Soluble;Ethanol:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.69 mM);DMSO:65 mg/mL (119.82 mM)

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p38MAPK, p38 MAPK, Inhibitor, inhibit, JNK2, JNK1, NF-κB, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NFkB, NF-kB, ERK1, ERK2, 7-O-Galloylsecologanol, 7-Galloylsecologanol, Cornuside, Comuside

Compound Identifiers

PubChem CID

11228694