Convallatoxin

SKU: orb1297411

Description

Convallatoxin is a naturally occurring cardiac glycoside. It is utilized in cardiovascular research for its role as a potent Na+/K+-ATPase inhibitor, with applications in studying heart failure mechanisms and cytotoxicity in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 508-75-8
• MW: 550.64
• Purity: 99.27% (May vary between batches)
• Formula: C₂₉H₄₂O₁₀
• SMILES: [H][C@@]12CC[C@]3(O)C[C@H](CC[C@]3(C=O)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
• Target: NF-κB|||P-gp|||PPAR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.63 mM);DMSO:50 mg/mL (90.8 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PPARγ, Peroxisome proliferator-activated receptors, PPAR, P-glycoprotein, P-gp (P-glycoprotein), Pgp, P-gp, substrate, psoriasis, MDR1, Inhibitor, inhibit, Multidrug resistance protein 1, inflammation, Nuclear factor-kappaB, Nuclear factor-κB, NF-κB, NFκB, NFkB, NF-kB, anti-inflammatory, anti-proliferative, ABCB1, Cluster of differentiation 243, colitic, CD243, Convallatoxin

Compound Identifiers

PubChem CID

441852