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pan-KRAS-IN-16

SKU: orb1685310

Description

3344 is a potent small molecule inhibitor that disrupts KRAS-effector interactions with a binding affinity of 126 nM. This compound is a valuable research tool for investigating KRAS-driven signaling pathways in both in vitro biochemical assays and in vivo cancer models, aiding the study of oncogenic RAS biology.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2368246-78-8
MW390.47
FormulaC24H26N2O3
SMILESO(C)C=1C=C(C2=C3C(=CC=C2)OCCO3)C=CC1NC4=CC(CN(C)C)=CC=C4
TargetKras,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information