Cobimetinib hemifumarate

SKU: orb1685865

Description

Cobimetinib hemifumarate is a selective MEK1 inhibitor exhibiting potent activity with an IC50 of 4.2 nM. It is widely used in oncology research, particularly for studying MAPK/ERK pathway signaling in various cancer cell lines and in vivo models of melanoma and other solid tumors.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1369665-02-0
• MW: 1178.707
• Formula: C₄₆H₄₆F₆I₂N₆O₈
• SMILES: OC(=O)\C=C\C(O)=O.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1
• Target: Apoptosis,Others,MEK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71491931