CMLD012612

SKU: orb1710016

Description

CMLD012612 is a potent small molecule inhibitor of eukaryotic initiation factor 4A (eIF4A), demonstrating cytotoxic activity with an IC50 of 2 nM in NIH/3T3 cells by disrupting protein synthesis. This compound is a valuable research tool for studying translation initiation mechanisms in cancer biology and cellular stress responses, applicable in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 2368900-35-8
• MW: 559.61
• Formula: C₃₁H₃₃N₃O₇
• SMILES: CON(C)C(=O)[C@@H]1[C@@H](c2ccccc2)[C@@]2(Oc3cc(OC)cc(OC)c3[C@@]22NC(C)=N[C@@]12O)c1ccc(OC)cc1
• Target: Others,PERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145712379