CML-07-119

SKU: orb3175059

Description

CML-07-119 is a selective inhibitor of GGPP synthase (GGPPS) with an IC50 value of approximately 27 nM. It induces apoptosis and exhibits anticancer activity against acute myeloid leukemia (AML) cells, including those with TP53 mutations. CML-07-119 also suppresses tumor growth in AML mouse xenograft models and is applicable in AML research.

Research Area

Cell Biology

Key Properties

• CAS Number: 2241548-12-7
• MW: 568.41
• Formula: C₂₁H₁₉FN₄O₈P₂S
• SMILES: O=C(NC1=CC=C(OC)C(F)=C1)C2=CC=CC(=C2)C=3N=C4SC=CC4=C(N3)NC(P(=O)(O)O)P(=O)(O)O
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis