CM121

SKU: orb1691138

Description

CM121 is a potent, reversible, and active-site directed inhibitor of ALDH1A2, with an IC50 of 0.54 µM and a Kd of 1.1 µM, mediated by hydrophobic interactions. This small molecule is a valuable chemical probe for studying retinoic acid biosynthesis in cancer stem cell biology and developmental research, applicable in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2204230-40-8
• MW: 460.48
• Formula: C₂₄H₁₇FN₄O₃S
• SMILES: CS(=O)(=O)c1ccc(cc1)-c1nn(cc1C(=O)Nc1cccc(F)c1)-c1ccc(cc1)C#N
• Target: Dehydrogenase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131955137