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CM-444

SKU: orb3134649

Description

CM-444 is an inhibitor of HDAC (IC50 ranging from 6 nM to 0.6 μM) and DNA methyltransferase (DNMT, IC50 ranging from 1.8 to 2.3 μM). This compound induces differentiation in acute myeloid leukemia cells, exhibits anti-leukemia activity, and enhances survival rates in mouse models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

FormulaC27H30N6O5
TargetDNA Methyltransferase,HDAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information