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Clozapine dihydrochloride

Clozapine dihydrochloride

Catalog Number: orb2814500

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Catalog Numberorb2814500
CategorySmall Molecules
DescriptionClozapine (HF 1854) dihydrochloride is utilized for researching psychiatric disorders. This compound exhibits high affinity for numerous neuroreceptors and acts as an effective antagonist of dopamine receptors, with a Ki value of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor, with Ki values of 9.5 nM and 4 nM, respectively. Additionally, Clozapine is a selective agonist of the muscarinic M4 receptor (EC50 = 11 nM).
MW399.75
CAS Number2711603-38-0
FormulaC18H21Cl3N4
SMILESClC1=CC=C2NC3=C(C(N4CCN(CC4)C)=NC2=C1)C=CC=C3.Cl.Cl
Storage-20°C
NoteFor research use only
  • Clozapine N-oxide dihydrochloride [orb1745121]

    98.11%

    2250025-93-3

    452.2

    C18H22Cl4N4O

    50 mg, 100 mg, 5 mg, 10 mg, 25 mg, 1 ml x 10 mM (in DMSO)