Cloxacillin sodium monohydrate

SKU: orb1310002

Description

Cloxacillin sodium monohydrate is a semisynthetic penicillin antibiotic resistant to beta-lactamase. It is widely used in research for its activity against Gram-positive bacteria, including in vitro susceptibility testing and in vivo models of staphylococcal infections.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 7081-44-9
• MW: 475.88
• Purity: 98.06%
• Formula: C₁₉H₁₇ClN₃NaO₅S·H₂O
• SMILES: [Na+].O.[C@H]12N([C@H](C(S2)(C)C)C(=O)[O-])C(=O)[C@H]1NC(=O)c1c(c2c(cccc2)Cl)noc1C
• Target: Antibacterial,Antibiotic
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.2 mM);H2O:50 mg/mL (105.07 mM);Ethanol:24 mg/mL (50.43 mM);DMSO:40 mg/mL (84.05 mM)

Bioactivity

• In Vivo:
  Prochlorperazine is showed to be able to induce antinociception in mice. prochlorperazine-treated mice show a complete integrity of motor co-ordination on the rota-rod test, normal spontaneous motility, as well as exploratory behaviour as revealed by the hole-board test. The antinociceptive effect of prochlorperazine appears to be due to the antagonism of D2 receptors since the increase of the pain threshold induced by the investigated compound is prevented by pretreatment with the D2 agonist quinpirole.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Hlα, MAPKs, NF-кB, Antibiotic, Bactopen, Bacterial, β-lactamase inhibitor, S. aureus peritonitis, RAW264.7

Compound Identifiers

PubChem CID

23675743