Closantel sodium

SKU: orb1224456

Description

A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases; also shows to be an allosteric inhibitor of SPAK and OSR1.Parasite Infection Approved(In Vitro):Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.

Key Properties

• CAS Number: 61438-64-0
• MW: 685.0555
• Purity: >98% (HPLC)
• Formula: C₂₂H₁₃Cl₂I₂N₂NaO₂
• SMILES: CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)O)Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na]
• Target: Parasite
• Solubility: 10 mM in DMSO

Bioactivity

• In Vitro:
  Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Parasite