Clorprenaline hydrochloride

SKU: orb1310794

Description

Clorprenaline hydrochloride is a selective β2-adrenergic receptor agonist used as a bronchodilator. It is employed in respiratory research to study airway smooth muscle relaxation and bronchoconstriction mechanisms in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 6933-90-0
• MW: 250.16
• Purity: >99.99% (May vary between batches)
• Formula: C₁₁H₁₇Cl₂NO
• SMILES: Cl.CC(C)NCC(O)c1ccccc1Cl
• Target: Adrenergic Receptor
• Solubility: H2O:46 mg/mL (183.88 mM);Ethanol:47 mg/mL (187.88 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.99 mM);DMSO:55 mg/mL (219.86 mM)

Bioactivity

• In Vivo:
  In a single chromatographic run, the linear range of clorprenaline was 8.0-1.6 × 103 ng/mL, with a limit of detection of 3.0 ng/mL. Clorprenaline is a bronchodilator that has been separated by affinity-interaction-based CE or charged CD-CZE sulfobutyl ether (SBE)-β-CD or β-CD -phosphates at a resolution greater than 1.2. Clorprenaline was separated under optimal conditions at 60 mM HP-β-CD. Clorprenaline hydrochloride, bromhexine hydrochloride, and deslorohydroxyzine hydrochloride are the three main ingredients of Clorprenaline compound tablets.
• In Vitro:
  The linear ranges 8.0-1.6 ×103 ng/mL for Clorprenaline in a single chromatographic run, the detection limits 3.0 ng/mL for Clorprenaline. Clorprenaline is a bronchodilator that has been separated by CE based on affinity-interaction or with charged CD-CZE sulfobuthylether (SBE)-β-CD or β-CD-phosphate with resolution greater than 1.2. Clorprenaline is separated in optimum condition of 60 mM HP-β-CD. Clorprenaline hydrochloride (a), bromhexine hydrochloride (b) and decloxizine hydrochloride (c) are three main components in clorprenaline compound tablet.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Clorprenaline, Clorprenaline HCl, Clorprenaline hydrochloride, Clorprenaline Hydrochloride, Beta Receptor, Adrenergic Receptor, AdrenergicReceptor, inhibit, NSC-334693, NSC334693, NSC 334693, Inhibitor, β-adrenergic receptor

Compound Identifiers

PubChem CID

23360