Clofarabine-5'-triphosphate

SKU: orb2814588

Description

Clofarabine-5'-triphosphate, the active phosphorylated metabolite of the anticancer agent Clofarabine, is generated intracellularly by deoxycytidine kinase. It functions as a potent inhibitor of DNA synthesis and repair, making it a critical tool for studying nucleotide metabolism and cytotoxicity in leukemia and solid tumor research, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 134646-41-6
• MW: 543.62
• Formula: C₁₀H₁₄ClFN₅O₁₂P₃
• SMILES: F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(Cl)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O
• Target: DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9915350