Clobetasol Propionate-d5

SKU: orb1737601

Description

Clobetasol propionate-d5 serves as an internal standard for GC-/LC-MS quantification of clobetasol propionate, a potent synthetic corticosteroid. This compound binds glucocorticoid receptors, inhibits human fibroblast proliferation in vitro, and demonstrates anti-inflammatory efficacy in vivo, such as reducing croton oil-induced edema in murine models, supporting research in dermatology and inflammation.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2280940-18-1
• MW: 472
• Formula: C₂₅H₂₇ClD₅FO₅
• SMILES: O(C(C(C([2H])([2H])[2H])([2H])[2H])=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
• Target: Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131708920