Cletoquine hydrochloride

SKU: orb1710030

Description

Cletoquine hydrochloride, a primary active metabolite and chloroquine derivative of hydroxychloroquine, demonstrates antimalarial activity and has shown antiviral efficacy against chikungunya virus (CHIKV) in research settings, supporting its investigation in virology and parasitology.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 159358-29-9
• MW: 344.28
• Purity: 98.40%
• Formula: C₁₆H₂₃Cl₂N₃O
• SMILES: ClC1=CC2=NC=CC(NC(CCCNCCO)C)=C2C=C1.Cl
• Target: Parasite,Influenza Virus
• Solubility: DMSO:4 mg/mL (11.62 mM)

Bioactivity

• In Vivo:
  Hydroxychloroquine (5 mg/kg; intravenously) is administered to BAL-/- mice for blood and tissue to determin the content of Cletoquine the tissue to blood concentration ratio (Kp) is ≥1, indicating accumulation of Cletoquine in tissues the Cletoquine Kp ratio fo the various tissues are observed of liver (114.3)>kidney (24.4)>spleen (19.3)>lungs (16.5)>heart (5.5.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Influenza virus, Influenza Virus, InfluenzaVirus, Parasite, Cletoquine Hydrochloride, Cletoquine hydrochloride( 4298-15-1 Free base)

Compound Identifiers

PubChem CID

168442593