Cleomiscosin A

SKU: orb1297420

Description

Cleomiscosin A, isolated from Acer okamotoanum, is a bioactive compound that inhibits TNF-α secretion in mouse peritoneal macrophages. It serves as a research tool for studying anti-inflammatory mechanisms and the prevention of LDL oxidation, relevant to atherosclerosis research in both in vitro and in vivo models.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 76948-72-6
• MW: 386.35
• Purity: >99.99% (May vary between batches)
• Formula: C₂₀H₁₈O₈
• SMILES: COc1cc(ccc1O)[C@H]1Oc2c(OC)cc3ccc(=O)oc3c2O[C@@H]1CO
• Target: TNF,Antioxidant,LDL
• Solubility: DMSO:1.9 mg/mL (4.92 mM)

Bioactivity

• In Vitro:
  Cleomiscosin A protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl with IC50s of 13.4 and 8.1 μM, respectively.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TNF-α, LDL, Antioxidant, Cleomiscosin A

Compound Identifiers

PubChem CID

442510