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Claturafenib
Catalog Number: orb2695470
Product Properties
| Catalog Number | orb2695470 |
|---|---|
| Category | Small Molecules |
| Description | Claturafenib (PF-07799933) is a brain-permeable, selective, all-mutant BRAF inhibitor with broad inhibitory effects on pERK levels in HT29 cells.Claturafenib has shown antitumor activity in preclinical studies in both BRAF V600- and non-V600-mutant cancers and can be used in combination with MEK inhibitors. |
| Target | Raf |
| Purity | 98.68% |
| MW | 490.31 |
| CAS Number | 2754408-94-9 |
| Formula | C18H15Cl2F2N5O3S |
| SMILES | O=C1C2=C(N=CN1C)C=CC(NC=3C(F)=CC=C(NS(=O)(=O)N4CC(F)C4)C3Cl)=C2Cl |
| Storage | -20°C |
| Research Area | Signal Transduction |
| Note | For research use only |
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