CL67

SKU: orb1702407

Description

CL67 is a small molecule inhibitor of the hypoxia-inducible factor (HIF) pathway. It functions by selectively binding to and stabilizing a G-quadruplex structure within the HIF-1α promoter, thereby suppressing its transcriptional activity in vitro. This mechanism makes it a valuable chemical probe for studying hypoxia signaling in cancer and cardiovascular research.

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 1401242-86-1
• MW: 670.81
• Formula: C₃₈H₄₂N₁₀O₂
• SMILES: N(C(CN(CC)CC)=O)C=1C=C(N2C=C(C3=CC4=C(C=CC(=C4)C5=CN(N=N5)C6=CC(NC(CN(CC)CC)=O)=CC=C6)C=C3)N=N2)C=CC1
• Target: HIF/HIF Prolyl-Hydroxylase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

66553183