CL5D

SKU: orb3135399

Description

CL5D is an activator of the protein deacetylase SIRT6. It significantly enhances the deacetylase activity and catalytic efficiency of SIRT6. CL5D modulates SIRT6 activity by promoting its conformational changes, particularly relying on the Arg-65 residue. This compound can be used to study the activation mechanism of SIRT6 and its roles in metabolism, DNA repair, and aging.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 2488745-53-3
• MW: 731.58
• Formula: C₂₉H₁₁Cl₇N₂O₆
• SMILES: O=C(O)C1=CC=C2C(=O)N(C(=O)C2=C1)C3=CC=C(C(Cl)=C3)N(C(=O)C=4C(Cl)=CC(Cl)=CC4Cl)C(=O)C=5C(Cl)=CC(Cl)=CC5Cl
• Target: Sirtuin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sirtuin