Cl-amidine TFA

SKU: orb1909581

Description

Cl-amidine TFA is a cell-permeable, orally bioavailable pan-PAD inhibitor with IC50 values of 0.8 μM (PAD1), 6.2 μM (PAD3), and 5.9 μM (PAD4). It is widely used in vitro to study PAD function in cancer models, where it induces apoptosis, and has demonstrated activity in preclinical in vivo studies for oncology and autoimmune disease research.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation

Key Properties

• CAS Number: 1043444-18-3
• MW: 424.8
• Purity: 98.11% (May vary between batches)
• Formula: C₁₆H₂₀ClF₃N₄O₄
• SMILES: C(C(O)=O)(F)(F)F.C(N[C@@H](CCCNC(CCl)=N)C(N)=O)(=O)C1=CC=CC=C1
• Target: MicroRNA,PAD,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57402549