CKLF1-C27

SKU: orb1981211

Description

CKLF1-C27 is a C-terminal peptide that acts as a CCR4 receptor agonist, activating the ERK1/2 pathway while antagonizing native CKLF1. It promotes HUVEC proliferation in vitro and is a valuable research tool for studying inflammatory processes, including potential applications in psoriasis research.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• Target: CCR,ERK
• CAS Number: 891861-48-6
• MW: 3196.78
• Formula: C₁₅₁H₂₄₃N₃₉O₃₇
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C(CNC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=C(O)C=C4)NC([C@@H](NC([C@@H](NC([C@H](C)N)=O)CC(C)C)=O)[C@H](CC)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(N)=O)=O)CCC2)CO)=O)=O)CCC1)CC5=CC=C(O)C=C5)=O)CCC(N)=O)=O)CCCCN)=O)CCCCN)(=O)N6[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C(C)C)=O)CCC(O)=O)=O)CCCCN)=O)CCCCN)=O)CCC(O)=O)=O)=O)C(C)C)=O)CCC6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652846