CK2-IN-9

SKU: orb1944513

Description

CK2-IN-9 is a highly potent and selective CK2 kinase inhibitor with an enzyme IC50 of 3 nM and a cellular Wnt pathway IC50 of 75 nM. Its pharmacokinetic profile in rats is characterized by high clearance and low systemic exposure. This inhibitor is a valuable chemical probe for studying CK2 and Wnt signaling roles in cancer and cellular processes in both in vitro and in vivo models.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1461658-58-1
• MW: 447.54
• Formula: C₂₃H₂₉N₉O
• SMILES: C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1
• Target: Wnt/beta-catenin,Others,Casein Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

76321032