cisVH 298

SKU: orb1690084

Description

cisVH 298 is an inactive analog of the VHL ligand VH 298, serving as a critical negative control in proteolysis-targeting chimera (PROTAC) and molecular glue research. It is utilized in both in vitro and in vivo studies to validate on-target effects by confirming the absence of VHL binding and subsequent degradation events.

Research Area

Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2097381-86-5
• MW: 523.65
• Formula: C₂₇H₃₃N₅O₄S
• SMILES: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1
• Target: Others,Ligands for E3 Ligase,HIF/HIF Prolyl-Hydroxylase,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

127021044