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Cisd2 agonist 2

SKU: orb1942051

Description

Cisd2 agonist 2 (compound 6) is a potent, orally bioavailable small molecule activator of Cisd2 (EC50=191 nM), a target implicated in nonalcoholic fatty liver disease (NAFLD). It has demonstrated in vivo efficacy without significant toxicity in Cisd2hKO-het mouse models, supporting its use in metabolic and liver disease research.

Research Area

Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number2916371-59-8
MW306.34
FormulaC14H14N2O4S
SMILESO=C(OC)C1=C(SC(C(=O)NC2=CC=C(O)C=C2)=C1C)N
TargetOthers,IKZF

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Cisd2 agonist 2 (orb1942051)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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