cis-V-11-0711

SKU: orb3173887

Description

cis-V-11-0711 is the cis form of V-11-0711, a potent and selective inhibitor of Chk-α with an IC50 of 20 nM. V-11-0711 significantly reduces PCho levels and can cause reversible growth arrest. At high concentrations, V-11-0711 induces apoptosis and is applicable in research on cervical cancer and triple-negative breast cancer.

Research Area

Cell Biology

Key Properties

• CAS Number: 1428338-79-7
• MW: 421.58
• Formula: C₂₇H₃₅NO₃
• SMILES: [C@@](CCC1=C(OC2CCOCC2)C=CC=C1)(O)([C@@]3(C4CCN(C3)CC4)[H])C5=CC=CC=C5
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis