cis-Lomibuvir

SKU: orb1983437

Description

Cis-Lomibuvir (cis-VX-222) is a potent and selective non-nucleoside inhibitor of the HCV NS5B RNA-dependent RNA polymerase, binding to thumb pocket 2 with high affinity. It demonstrates strong antiviral activity in HCV replicon assays and is a valuable tool for studying HCV replication mechanisms and inhibitor resistance in vitro.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 1026785-59-0
• MW: 445.61
• Purity: 99.85% (May vary between batches)
• Formula: C₂₅H₃₅NO₄S
• SMILES: N(C(=O)[C@@H]1CC[C@@H](C)CC1)(C2=C(C(O)=O)SC(C#CC(C)(C)C)=C2)[C@@H]3CC[C@H](O)CC3
• Target: HCV Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24798764