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Cinnamic aldehyde

SKU: orb1222698

Description

Cinnamic aldehyde exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. Cinnamic aldehyde induces apoptosis of CML cells in vitro, down-regulation of the expression and function of BCR-ABL may be one of its most important anti-leukemia mechanisms. Cinnamic aldehyde and cinnamic acid are cardioprotective in a rat model of ischemic myocardial injury, the mechanism is related to anti-oxidative and anti-inflammatory properties.(In Vitro):trans-cinnamaldehyde -β-cyclodextrin complex against Salmonella spp. and Lis-teria spp. with minimum inhibitory concentrations ranging from 10 to 20 mg/mL, respectively.

Images & Validation

Key Properties

CAS Number14371-10-9
MW132.16
Purity>98% (HPLC)
FormulaC9H8O
SMILESC1=CC=C(C=C1)C=CC=O
TargetCOX-2
SolubilityIn Vitro: DMSO : 50 mg/mL (378.33 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Cinnamic aldehyde (orb1222698)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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