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Cimicifugic acid D

SKU: orb3141889

Description

Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyl tartaric acid ester that can induce vasorelaxation and an endothelium-dependent relaxation mechanism in pre-constricted rat aortic strips. During norepinephrine-induced contractions in rat aortic strips, Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC), while it does not affect voltage-dependent Ca2+ channels (VDC) or K+-induced contractions.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number219986-51-3
MW418.35
FormulaC20H18O10
SMILES[C@@H]([C@](CC1=CC=C(O)C=C1)(C(O)=O)O)(OC(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=O
TargetCalcium Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information