Cilostamide

SKU: orb1299633

Description

Cilostamide (OPC3689) is a potent and selective inhibitor of phosphodiesterase 3A and 3B, with IC50 values of 27 nM and 50 nM, respectively. This compound is a valuable research tool for studying cAMP signaling in cardiovascular function, platelet aggregation, and lipolysis in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 68550-75-4
• MW: 342.44
• Purity: >98%
• Formula: C₂₀H₂₆N₂O₃
• SMILES: CN(C1CCCCC1)C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1
• Target: PDE (Phosphodiesterase)
• Solubility: Soluble in DMSO (up to 30 mg/ml).

Bioactivity

• Target IC50:
  PDE3A:27 nM |PDE3B:50 nM

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OPC-3689

Compound Identifiers

PubChem CID

2753