Cilengitide TFA

SKU: orb1908980

Description

Cilengitide is a potent and selective cyclic RGD pentapeptide inhibitor of αvβ3 and αvβ5 integrins, with IC50 values of 4.1 nM and 79 nM, respectively. It has been widely used in preclinical in vitro and in vivo research to study angiogenesis, tumor growth, and metastasis in various cancer models.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 199807-35-7
• MW: 702.68
• Formula: C₂₉H₄₁F₃N₈O₉
• SMILES: OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
• Target: Integrin|||Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129626550